Graves Disease Symptoms

The Graves disease is the most frequent source of hyperthyroidism. The clinical Graves Disease Symptoms are as follows:

  • General disorders: Related to excessive thermogenesis and increased sensitivity to heat and excessive sweating that is warm and widespread. Also fatigue, polyuria, polydipsia and weight loss or increased appetite preserved.
  • Skin and Appendages: Skin lukewarm and moist by vasodilation and sweating. Some may have vitiligo and infiltrative dermopathy or pretibial myxedema (autoimmune). Sometimes thin and fragile hair and nails soft and friable. Sometimes plummer nails (onycholysis with disconnection of the nail’s distal part from the nail bed).
  • Circulatory system: decreased peripheral vascular resistance and increased spending by increasing VS and HR. FA bounding pulse and it is very common in the elderly. Patients with Graves most often present mitral valve prolapse.
  • Gastrointestinal: Increased frequency and stool consistency less. In some ways there may be alterations in liver enzymes and in severe cases may appear enlarged liver and jaundice.
    • Graves Disease Symptoms
  • Blood and hematopoietic system: NC and NC anemia, pernicious anemia may have association representing an autoimmune process. In severe cases there may be splenomegaly and lymphadenopathy.
  • Nervous and muscular systems: nervousness, agitation, restlessness, taquilalia, hyperkinesia and emotional lability. Hyperactive although limited by their fatigability (muscular in origin and insomnia). Exceptionally reactions manic-depressive, schizoid or paranoid. Tremor (arms outstretched, tongue, eyelids half-closed). Tendon reflexes quick. Muscle disorder is common, often proximal fatiguability but can reach thyrotoxic myopathy. Association between Graves disease and myasthenia gravis. A rare complication is the periodic paralysis that occurs with hypokalemia during the crisis and appears in males, especially in the East.